Protein Modification Reagents
Broadpharm Mal-PEG6-NHS ester | 1599472-25-9 | MFCD20926374 | 100mg
Mal-PEG6-NHS ester | Putity: 98% | MW: 530.5 | 1599472-25-9 | MFCD20926374 | 100mg
eMolecules Combi-Blocks Acetylene-PEG4-biotin conjugate 250mg 415498461 QG-7572 95 000 1458576-00-5 MFCD22380755 457 590 C21H35N3O6S
Combi-Blocks Acetylene-PEG4-biotin conjugate 250mg 415498461 QG-7572 95 000 1458576-00-5 MFCD22380755 457 590 C21H35N3O6S
Medchemexpress LLC Bis-PEG4-TFP ester | 1446282-42-3 | MFCD21363292 | 98.0% | 590.41 | C24H22F8O8 | 25 MG
Bis-PEG4-TFP ester is a bifunctional PEG-based linker bearing tetrafluorophenyl (TFP) activated esters at both ends, designed for conjugation to amine-containing ligands during PROTAC and bioconjugation synthesis. Supplied as a liquid in small research-scale quantities, it is intended for research use only and should be stored under recommended conditions to maintain stability.
- Provides bifunctional TFP-activated esters for efficient amide coupling.
- PEG4 spacer offers a flexible, hydrophilic linker with defined length.
- High purity suitable for laboratory research and synthesis.
- Liquid form facilitates accurate handling and aliquoting.
- Storage recommendations support extended stability when protected from light and moisture.
Medchemexpress LLC 8-Arm PEG-COOH (MW 20000) | 98.0% | 20000 (Average) | 5 MG
8-Arm PEG-COOH (MW 20000) is a compound composed of PEG units and carboxyl (-COOH) groups, which can be used for drug delivery. It is suitable for biochemical assay reagents and can be stored at -20°C, protected from light.
- Composed of PEG units and carboxyl (-COOH) groups
- Suitable for drug delivery applications
- Used as biochemical assay reagents
- Stable under recommended storage conditions
Medchemexpress LLC (S,R,S)-AHPC-PEG5-Boc | 2923734-82-9 | 95.3% | 807.01 g/mol | C40H62N4O11S | 5 MG
(S,R,S)-AHPC-PEG5-Boc is an E3 ligase ligand-linker conjugate that combines an (S,R,S)-AHPC-derived VHL ligand with a PEG5 spacer and a Boc protecting group. It is designed for use in targeted protein degradation research and PROTAC synthesis, and is supplied at high purity for medicinal chemistry applications. CAS 2923734-82-9, molecular weight 807.01 g/mol, purity ≈95.3%.
- Boc-protected VHL ligand-linker conjugate suitable for PROTAC development.
- Peg5 linker provides flexible spacing for bifunctional molecule design.
- High purity supports medicinal chemistry and analytical work.
- Available in small mass quantities to support discovery research.
- Soluble in DMSO for convenient formulation and handling.
- Stable when stored cold under inert atmosphere for longer-term storage.
Medchemexpress LLC DBCO-PEG4-NHS ester | 1427004-19-0 | 99.0% | C34H39N3O10 | 500 MG
DBCO-PEG4-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing a DBCO group that facilitates strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules possessing Azide groups. PROTACs leverage the intracellular ubiquitin-proteasome system for the selective degradation of target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group for strain-promoted alkyne-azide cycloaddition (SPAAC)
Medchemexpress LLC Bis-PEG4-PFP ester | 1314378-12-5 | 97.0% | 5 G
Bis-PEG4-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is for research use only and not sold to patients.
- Appears as a colorless to light yellow liquid with a density of 1.473 g/cm³.
- PROTACs consist of two different ligands connected by a linker.
- One ligand targets an E3 ubiquitin ligase, and the other targets a protein of interest.
- PROTACs work by leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Medchemexpress LLC DBCO-PEG24-NHS ester | 2765066-38-2 | MFCD34551889 | 95.5% | 1530.74 | C74H119N3O30 | 10 MG
DBCO-PEG24-NHS ester is a bifunctional polyethylene glycol (PEG) reagent containing a dibenzocyclooctyne (DBCO) group and an N-hydroxysuccinimide (NHS) ester. It is designed for bioconjugation workflows where copper-free click chemistry and selective amine coupling are required; the PEG24 spacer increases water solubility and reduces steric hindrance. Supplied for research use with documented purity and recommended storage conditions.
- Enables copper-free click chemistry via DBCO-mediated SPAAC.
- Reacts selectively with primary amines through NHS ester chemistry.
- Provides a PEG24 spacer to increase water solubility and flexibility.
- Supplied with documented purity and certificate of analysis.
- Stable when stored sealed, away from moisture and light under recommended temperatures.
- Available in small research-scale quantities.